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Karyopharm Therapeutics Inc (KPTI) Insider Trading

Total insider buys:
  • $10,245,912.22
Total insider sells:
  • $142,179,299.35
Most recent insider trade:
  • Sept. 15, 2025
Most active insider trader:
  • Ltd Chione
Trader NameDateTitleAmountPriceTypeTotal Value
Feb. 20, 2018CEO10,000$14.79Sell$147,900.00
Feb. 16, 2018EVP2,500$15.01Sell$37,525.00
Feb. 7, 2018Insider10,000$12.50Sell$125,000.00
Feb. 7, 2018EVP1,500$13.00Sell$19,500.00
Jan. 18, 2018CEO10,000$10.09Sell$100,900.00
Jan. 8, 2018Insider10,000$10.08Sell$100,800.00
Dec. 18, 2017CEO10,000$9.16Sell$91,600.00
Dec. 12, 2017SVP27,042$10.28Sell$277,991.76
Dec. 7, 2017Insider10,000$10.39Sell$103,900.00
Nov. 7, 2017SVP4,958$11.25Sell$55,777.50
Oct. 2, 2017SVP1,500$12.00Sell$18,000.00
Oct. 2, 2017Director2,000$12.00Sell$24,000.00
Sept. 15, 2017SVP2,000$11.00Sell$22,000.00
Sept. 15, 2017Director2,882$11.00Sell$31,702.00
Sept. 11, 2017Director118$11.00Sell$1,298.00
Aug. 29, 2017SVP2,195$10.00Sell$21,950.00
June 26, 2017SVP805$10.03Sell$8,074.15
Nov. 14, 2016Insider3,309$10.06Sell$33,288.54
June 23, 2016Major Shareholder18,824$8.03Sell$151,156.72
June 13, 2016Major Shareholder7,074$8.51Sell$60,199.74
June 9, 2016Major Shareholder45,541$9.21Sell$419,432.61
June 7, 2016Major Shareholder40,000$9.24Sell$369,600.00
June 2, 2016Major Shareholder17,855$9.65Sell$172,300.75
June 1, 2016Major Shareholder74,664$9.61Sell$717,521.04
May 31, 2016Major Shareholder17,096$9.66Sell$165,147.36
May 27, 2016Major Shareholder40,000$9.58Sell$383,200.00
May 26, 2016Major Shareholder46,122$9.73Sell$448,767.06
May 23, 2016Major Shareholder93,932$8.54Sell$802,179.28
May 18, 2016Major Shareholder63,800$8.15Sell$519,970.00
May 16, 2016Major Shareholder10,400$8.01Sell$83,304.00
May 11, 2016Major Shareholder31,868$8.24Sell$262,592.32
Dec. 8, 2015Director15,000$15.01Sell$225,150.00
April 7, 2015EVP3,000$31.81Buy$95,430.00
April 2, 2015Director3,000$29.31Buy$87,930.00
April 2, 2015CFO5,000$29.71Buy$148,550.00
Jan. 12, 2015CEO50,000$33.00Sell$1,650,000.00
Jan. 12, 2015Director45,454$33.00Buy$1,499,982.00
Jan. 12, 2015Insider25,000$33.00Sell$825,000.00
Dec. 2, 2014Director10,000$43.52Sell$435,200.00
Dec. 1, 2014Major Shareholder278,115$41.92Sell$11,658,580.80
Nov. 25, 2014Major Shareholder242,800$42.40Sell$10,294,720.00
Nov. 19, 2014Major Shareholder65,968$40.09Sell$2,644,657.12
Nov. 12, 2014Major Shareholder164,100$42.83Sell$7,028,403.00
Nov. 11, 2014Major Shareholder54,100$42.51Sell$2,299,791.00
Nov. 10, 2014Major Shareholder65,000$43.40Sell$2,821,000.00
Nov. 10, 2014Director5,000$45.05Sell$225,250.00
Nov. 6, 2014Major Shareholder272,784$42.11Sell$11,486,934.24
Oct. 29, 2014Director3,500$40.05Sell$140,175.00
Sept. 26, 2014Major Shareholder50,000$42.54Sell$2,127,000.00
Sept. 24, 2014Major Shareholder22,498$40.32Sell$907,119.36
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  • Insiders are both buying and selling Karyopharm Therapeutics Inc stock.

  • The insider traders at Karyopharm Therapeutics Inc are: Ltd Chione, Michael Kauffman, Sharon Shacham, Richard A Paulson, Christopher Brett Primiano, Mansoor Raza Mirza, Marcin Czernik, Michael Mason, Deepika Pakianathan, Stuart Poulton, Sohanya Roshan Cheng, Jatin Shah, Reshma Rangwala, Ran Frenkel, Kristin Abate, Michael Mano, Garen G Bohlin, Stephen Mitchener, Tanya Lewis, John Demaree, Justin A Renz, Ltd Plio, Paul Brannelly, Paulson Richard A., and Barry E Greene

  • The most active insider trader at Karyopharm Therapeutics Inc is Ltd Chione with 36 trades.

  • Ltd Chione has sold the most Karyopharm Therapeutics Inc stock with a total value of $91,689,798.39.

  • Deepika Pakianathan has bought the most Karyopharm Therapeutics Inc stock with a total value of $10,995,453.42.

  • The most recent insider trade for Karyopharm Therapeutics Inc was on Sept. 15, 2025.

  • The single biggest insider buy for Karyopharm Therapeutics Inc was from Deepika Pakianathan with a total value of $5,000,000.00 on Nov. 12, 2013.

  • The single biggest insider sell for Karyopharm Therapeutics Inc was from Ltd Plio with a total value of $17,770,000.00 on July 23, 2014.