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Karyopharm Therapeutics Inc (KPTI) Insider Trading

Total insider buys:
  • $10,245,912.22
Total insider sells:
  • $142,179,299.35
Most recent insider trade:
  • Sept. 15, 2025
Most active insider trader:
  • Ltd Chione
Trader NameDateTitleAmountPriceTypeTotal Value
Dec. 9, 2019CEO10,000$17.02Sell$170,200.00
Dec. 9, 2019Director10,342$17.02Sell$176,020.84
Dec. 6, 2019EVP13,000$17.45Sell$226,850.00
Nov. 11, 2019Insider20,000$15.60Sell$312,000.00
Nov. 11, 2019CEO10,000$14.76Sell$147,600.00
Nov. 8, 2019CEO10,000$14.63Sell$146,300.00
Nov. 1, 2019CEO20,000$14.17Sell$283,400.00
Nov. 1, 2019Insider10,000$12.00Sell$120,000.00
Sept. 16, 2019CEO10,000$12.00Sell$120,000.00
Sept. 16, 2019Insider20,000$12.00Sell$240,000.00
Feb. 27, 2019Major Shareholder1,481,643$4.81Sell$7,126,702.83
Feb. 25, 2019Major Shareholder800,000$4.99Sell$3,992,000.00
Jan. 7, 2019Insider12,500$10.23Sell$127,875.00
Dec. 7, 2018Insider12,500$10.11Sell$126,375.00
Nov. 26, 2018CEO9,600$11.00Sell$105,600.00
Nov. 19, 2018Insider400$11.14Sell$4,456.00
Nov. 7, 2018Insider12,500$11.65Sell$145,625.00
Oct. 18, 2018Insider10,000$12.63Sell$126,300.00
Oct. 8, 2018Insider12,500$15.75Sell$196,875.00
Sept. 18, 2018CEO10,000$18.26Sell$182,600.00
Sept. 10, 2018EVP10,000$18.90Sell$189,000.00
Sept. 7, 2018Insider12,500$19.31Sell$241,375.00
Sept. 6, 2018Major Shareholder164,800$21.05Sell$3,469,040.00
Sept. 4, 2018Major Shareholder251,468$20.94Sell$5,265,739.92
Aug. 31, 2018Major Shareholder11,468$21.05Sell$241,401.40
Aug. 29, 2018Major Shareholder214,026$19.52Sell$4,177,787.52
Aug. 29, 2018Director2,500$20.00Sell$50,000.00
Aug. 27, 2018Major Shareholder14,026$18.52Sell$259,761.52
Aug. 20, 2018CEO10,000$17.46Sell$174,600.00
Aug. 9, 2018Major Shareholder80,876$18.52Sell$1,497,823.52
Aug. 7, 2018CEO12,500$18.04Sell$225,500.00
Aug. 7, 2018Major Shareholder10,602$18.60Sell$197,197.20
July 25, 2018Major Shareholder30,039$18.65Sell$560,227.35
July 23, 2018Major Shareholder20,000$18.66Sell$373,200.00
July 20, 2018Major Shareholder126,742$18.97Sell$2,404,295.74
July 18, 2018Major Shareholder50,000$18.52Sell$926,000.00
July 18, 2018CEO10,000$18.27Sell$182,700.00
July 16, 2018Major Shareholder2,654$18.52Sell$49,152.08
July 9, 2018Insider12,500$18.72Sell$234,000.00
June 18, 2018Insider10,000$18.66Sell$186,600.00
June 7, 2018Insider10,000$17.30Sell$173,000.00
May 18, 2018CEO10,000$19.39Sell$193,900.00
May 10, 2018EVP2,000$18.01Sell$36,020.00
May 7, 2018Insider10,000$16.77Sell$167,700.00
April 18, 2018CEO10,000$14.79Sell$147,900.00
April 9, 2018Insider10,000$12.48Sell$124,800.00
March 19, 2018CEO10,000$15.29Sell$152,900.00
March 12, 2018Director2,500$17.01Sell$42,525.00
March 7, 2018Insider10,000$16.15Sell$161,500.00
March 5, 2018EVP2,500$16.03Sell$40,075.00
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  • Insiders are both buying and selling Karyopharm Therapeutics Inc stock.

  • The insider traders at Karyopharm Therapeutics Inc are: Ltd Chione, Michael Kauffman, Sharon Shacham, Richard A Paulson, Christopher Brett Primiano, Mansoor Raza Mirza, Marcin Czernik, Michael Mason, Deepika Pakianathan, Stuart Poulton, Sohanya Roshan Cheng, Jatin Shah, Reshma Rangwala, Ran Frenkel, Kristin Abate, Michael Mano, Garen G Bohlin, Stephen Mitchener, Tanya Lewis, John Demaree, Justin A Renz, Ltd Plio, Paul Brannelly, Paulson Richard A., and Barry E Greene

  • The most active insider trader at Karyopharm Therapeutics Inc is Ltd Chione with 36 trades.

  • Ltd Chione has sold the most Karyopharm Therapeutics Inc stock with a total value of $91,689,798.39.

  • Deepika Pakianathan has bought the most Karyopharm Therapeutics Inc stock with a total value of $10,995,453.42.

  • The most recent insider trade for Karyopharm Therapeutics Inc was on Sept. 15, 2025.

  • The single biggest insider buy for Karyopharm Therapeutics Inc was from Deepika Pakianathan with a total value of $5,000,000.00 on Nov. 12, 2013.

  • The single biggest insider sell for Karyopharm Therapeutics Inc was from Ltd Plio with a total value of $17,770,000.00 on July 23, 2014.